RT Journal Article
SR Electronic
T1 Acute pulmonary embolism in a child with ANCA-negative idiopathic pulmonary capillaritis
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 610
OP 613
DO 10.15537/smj.2019.6.24210
VO 40
IS 6
A1 Asseri, Ali A.
A1 Zeng, Yi
A1 Daines, Cori L.
YR 2019
UL http://smj.org.sa/content/40/6/610.abstract
AB Diffuse alveolar hemorrhage is an uncommon and often fatal condition in children that is characterized by distinct histopathological etiologies. Herein, we discuss the case of an 11-year-old girl who presented with acute worsening of hypoxia and left-sided chest pain. The patient had lung biopsy-proven idiopathic pulmonary capillaritis and was being treated with prednisolone every alternate day, azathioprine, and hydroxychloroquine. A contrast-computed tomography (CT) scan of the chest showed an acute left lower-lobe pulmonary embolism. Negative results were obtained on a test for thrombophilia. In children, pulmonary embolism with anti-neutrophil cytoplasmic antibody-negative idiopathic pulmonary capillaritis is a rare clinical condition. The exact cause of thrombus formation in this case is unknown; however, obesity, immobility, and chronic systemic corticosteroid therapy probably played a role.