RT Journal Article SR Electronic T1 Is a history of cesarean section a risk factor for abnormal uterine bleeding in patients with uterine leiomyoma? JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 871 OP 876 DO 10.15537/smj.2016.8.14711 VO 37 IS 8 A1 Kinay, Tugba A1 Basarir, Zehra O. A1 Tuncer, Serap F. A1 Akpinar, Funda A1 Kayikcioglu, Fulya A1 Koc, Sevgi A1 Karakaya, Jale YR 2016 UL http://smj.org.sa/content/37/8/871.abstract AB Objectives: To determine whether a history of cesarean section was a risk factor for abnormal uterine bleeding in patients with uterine leiomyomas, and to identify other risk factors for this symptom.Methods: We analyzed retrospectively, the medical records of patients who underwent hysterectomies due to the presence of uterine leiomyomas during a 6-year period (2009 and 2014) at Etlik Zubeyde Hanim Women’s Health Training and Research Hospital, Ankara, Turkey. Uterine leiomyoma was diagnosed based on histopathological examination of hysterectomy specimens. Demographic characteristics, and laboratory and histopathological findings were compared between patients with uterine leiomyoma with and without abnormal uterine bleeding.Results: In total, 501 (57.9%) patients had abnormal uterine bleeding and 364 (42.1%) patients had other symptoms. A history of cesarean section was more common in patients with abnormal uterine bleeding than in those with other symptoms (17.6% versus 9.3%, p=0.001; odds ratio [OR]: 2.1; 95% confidence interval [CI]: 1.4-3.3). The presence of a submucosal leiomyoma (OR: 2.1; 95% CI: 1.5-3.1) and coexistent adenomyosis (OR: 1.6; 95% CI: 1.1-2.4) were also associated with abnormal uterine bleeding.Conclusion: A history of cesarean section was an independent risk factor for abnormal uterine bleeding in patients with uterine leiomyomas; submucosal leiomyoma and coexisting adenomyosis were also independent risk factors.