PT  - JOURNAL ARTICLE
AU  - Sahin, Muslum
AU  - Acar, Goksel
AU  - Kalkan, Mehmet E.
AU  - Acar, Rezzan D.
AU  - Kilicgedik, Alev
AU  - Teymen, Burak
AU  - Arslantas, Ugur
AU  - Kirma, Cevat
TI  - Thrombus aspiration during primary percutaneous coronary intervention associated with reduced platelet activation
AID  - 10.15537/smj.2015.8.11705
DP  - 2015 Aug 01
TA  - Saudi Medical Journal
PG  - 935--939
VI  - 36
IP  - 8
4099  - http://smj.org.sa/content/36/8/935.short
4100  - http://smj.org.sa/content/36/8/935.full
SO  - Saudi Med J2015 Aug 01; 36
AB  - Objectives: To determine the effect of thrombectomy on platelet function in patients undergoing primary percutaneous coronary intervention (PPCI) for ST segment elevation myocardial infarction (STEMI).Methods: This retrospective study included 413 consecutive STEMI patients who underwent PPCI between March 2012 and September 2013 at Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey that were assigned to the thrombus aspiration (TA) group or the non-TA group. Platelet count and mean platelet volume (MPV) were obtained at baseline and 24 hours (h), 48 h, and 72 h post PPCI.Results: Baseline MPV was similar in both groups, whereas the baseline platelet count was higher in the TA group (p=0.42 and p=0.002). The platelet count was higher in the TA group 24 h post PPCI (p=0.02), but was similar in both groups 48 h and 72 h post PPCI (p=0.18 and p=0.07). The MPV 48 h and 72 h post PPCI was higher in the non-TA group than in the TA group (8.4 ± 1.3 fL versus 8.7 ± 1.6 fL [p=0.04] and 8.5 ± 1.1 fL versus 8.9 ± 1.5 fL [p=0.04]).Conclusion: Thrombectomy reduced platelet activity via removal of thrombi from the coronary arteries in patients undergoing PPCI for STEMI.