RT Journal Article
SR Electronic
T1 Thrombus aspiration during primary percutaneous coronary intervention associated with reduced platelet activation
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 935
OP 939
DO 10.15537/smj.2015.8.11705
VO 36
IS 8
A1 Muslum Sahin
A1 Goksel Acar
A1 Mehmet E. Kalkan
A1 Rezzan D. Acar
A1 Alev Kilicgedik
A1 Burak Teymen
A1 Ugur Arslantas
A1 Cevat Kirma
YR 2015
UL http://smj.org.sa/content/36/8/935.abstract
AB Objectives: To determine the effect of thrombectomy on platelet function in patients undergoing primary percutaneous coronary intervention (PPCI) for ST segment elevation myocardial infarction (STEMI).Methods: This retrospective study included 413 consecutive STEMI patients who underwent PPCI between March 2012 and September 2013 at Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey that were assigned to the thrombus aspiration (TA) group or the non-TA group. Platelet count and mean platelet volume (MPV) were obtained at baseline and 24 hours (h), 48 h, and 72 h post PPCI.Results: Baseline MPV was similar in both groups, whereas the baseline platelet count was higher in the TA group (p=0.42 and p=0.002). The platelet count was higher in the TA group 24 h post PPCI (p=0.02), but was similar in both groups 48 h and 72 h post PPCI (p=0.18 and p=0.07). The MPV 48 h and 72 h post PPCI was higher in the non-TA group than in the TA group (8.4 ± 1.3 fL versus 8.7 ± 1.6 fL [p=0.04] and 8.5 ± 1.1 fL versus 8.9 ± 1.5 fL [p=0.04]).Conclusion: Thrombectomy reduced platelet activity via removal of thrombi from the coronary arteries in patients undergoing PPCI for STEMI.