PT  - JOURNAL ARTICLE
AU  - Mısır, A. Ferhat
AU  - Durmuşlar, Mustafa C.
AU  - Zerener, Tamer
AU  - Gün, Banu D.
TI  - Primary malignant melanoma
AID  - 10.15537/smj.2016.4.15017
DP  - 2016 Apr 01
TA  - Saudi Medical Journal
PG  - 446--449
VI  - 37
IP  - 4
4099  - http://smj.org.sa/content/37/4/446.short
4100  - http://smj.org.sa/content/37/4/446.full
SO  - Saudi Med J2016 Apr 01; 37
AB  - Malignant melanomas (MM) of the oral cavity are extremely rare, accounting for 0.2% to 8.0% of all malignant melanomas. Malignant melanomas is more frequently seen at the level of the hard palate and gingiva. Early diagnosis and treatment are important for reducing morbidity. Malignant melanoma cells stain positively with antibodies to human melanoma black 45, S-100 protein, and vimentin; therefore, immunohistochemistry can play an important role in evaluating the depth of invasion and the location of metastases. A 76-year-old man developed an oral malignant melanoma, which was originally diagnosed as a bluish reactive denture hyperplasia caused by an ill-fitting lower denture. The tumor was removed surgically, and histopathological examination revealed a nodular-type MM. There was no evidence of recurrence over a 4-year follow-up period.