RT Journal Article
SR Electronic
T1 Primary malignant melanoma
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 446
OP 449
DO 10.15537/smj.2016.4.15017
VO 37
IS 4
A1 Mısır, A. Ferhat
A1 Durmuşlar, Mustafa C.
A1 Zerener, Tamer
A1 Gün, Banu D.
YR 2016
UL http://smj.org.sa/content/37/4/446.abstract
AB Malignant melanomas (MM) of the oral cavity are extremely rare, accounting for 0.2% to 8.0% of all malignant melanomas. Malignant melanomas is more frequently seen at the level of the hard palate and gingiva. Early diagnosis and treatment are important for reducing morbidity. Malignant melanoma cells stain positively with antibodies to human melanoma black 45, S-100 protein, and vimentin; therefore, immunohistochemistry can play an important role in evaluating the depth of invasion and the location of metastases. A 76-year-old man developed an oral malignant melanoma, which was originally diagnosed as a bluish reactive denture hyperplasia caused by an ill-fitting lower denture. The tumor was removed surgically, and histopathological examination revealed a nodular-type MM. There was no evidence of recurrence over a 4-year follow-up period.