PT  - JOURNAL ARTICLE
AU  - Metin, Melike R.
AU  - Aydın, Hasan
AU  - Çetin, Hüseyin
AU  - Özmen, Evrim
AU  - Kayaçetin, Serra
TI  - The efficacy of diffusion weighted imaging and apparent diffusion coefficients mapping for liver metastasis of colonic adenocarcinomas
AID  - 10.15537/smj.2016.4.14921
DP  - 2016 Apr 01
TA  - Saudi Medical Journal
PG  - 379--385
VI  - 37
IP  - 4
4099  - http://smj.org.sa/content/37/4/379.short
4100  - http://smj.org.sa/content/37/4/379.full
SO  - Saudi Med J2016 Apr 01; 37
AB  - Objectives: To establish retrospectively the relation between the histopathologic grade of colorectal liver metastasis and apparent diffusion coefficient (ADC) values of hepatic metastases of colorectal adenocarcinomas.Methods: The diagnoses of liver metastases were confirmed with biopsy, surgery, and follow-up imaging findings. Twenty-six patients with 94 liver metastasis were included in the study. Of 94 masses, 59 were poorly-differentiated adenocarcinoma, 18 were moderately-differentiated adenocarcinoma, and 17 were well-differentiated regarding the diameters, ADC values, and ratio index (RI) values. Kolmogorov-smirnov normality test, Kruskal-wallis analysis of variance, Mann-Whitney U test with Bonferroni correction, Spearman correlation analysis, and receiver operating characteristics curve methods were applied to evaluate the statistical relations.Results: There was a statistically significant difference in terms of ADC values and RI between poorly-differentiated adenocarcinoma and moderately-differentiated adenocarcinoma plus well-differentiated adenocarcinomas. Poorly-differentiated adenocarcinomas have the lowest ADC values and highest RI values among other groups.Conclusion: Use of ADC values alone can be executed for the diagnosis of focal hepatic masses and also can aid in the differentiation of benign and malignant hepatic lesions.