RT Journal Article SR Electronic T1 The Saudi clinical practice guideline for the management of overweight and obesity in adults JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1151 OP 1162 DO 10.15537/smj.2016.10.14353 VO 37 IS 10 A1 Assim A. Alfadda A1 Madhawi M. Al-Dhwayan A1 Abdulhameed A. Alharbi A1 Basema K. Al Khudhair A1 Omar M. Al Nozha A1 Nawal M. Al-Qahtani A1 Saad H. Alzahrani A1 Wedad M. Bardisi A1 Reem M. Sallam A1 John J. Riva A1 Jan L. Brożek A1 Holger J. Schünemann A1 Ainsley Moore YR 2016 UL http://smj.org.sa/content/37/10/1151.abstract AB Objective: To assist healthcare providers in evidence-based clinical decision-making for the management of overweight and obese adults in Saudi Arabia.Methods: The Ministry of Health, Riyadh, Kingdom of Saudi Arabia assembled an expert Saudi panel to produce this clinical practice guideline in 2015. In collaboration with the methodological working group from McMaster University, Hamilton, Canada, using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, which describes both the strength of recommendation and the quality of evidenceResults: After identifying 11 questions, corresponding recommendations were agreed upon as guidance for the management of overweight and obese adults. These included strong recommendations in support of lifestyle interventions rather than usual care alone, individualized counseling interventions rather than generic educational pamphlets, physical activity rather than no physical activity, and physical activity in addition to diet rather than diet alone. Metformin and orlistat were suggested as conditional recommendations for the management of overweight and obesity in adults. Bariatric surgery was recommended, conditionally, for the management of obese adults (body mass index of ≥40 or ≥35 kg/m2 with comorbidities).Conclusions: The current guideline includes recommendation for the non-pharmacological, pharmacological, and surgical management of overweight and obese adults. In addition, the panel recommends conducting research priorities regarding lifestyle interventions and economic analysis of drug therapy within the Saudi context, as well as long term benefits and harms of bariatric surgery.