%0 Journal Article %A Jinnan Ou %A Huaying Chen %A Lezhi Li %A Liping Zhao %A Na Nie %T The role of non-invasive ventilation used immediately after planned extubation for adults with chronic respiratory disorders %D 2018 %R 10.15537/smj.2018.2.21942 %J Saudi Medical Journal %P 131-136 %V 39 %N 2 %X Objectives: To estimate the benefits of non-invasive ventilation (NIV) used immediately after planned postextubation in patients with chronic respiratory disorders.Methods: Cochrane Library, PubMed, the Chinese BioMedical Literature Database of clinical trials (CBD) and Embase were searched for pertinent studies by 2 trained investigators. Pooled odds ratios and 95% confidence intervals (CIs) were calculated by employing both fixed-effects and random-effects models.Results: Eight studies enrolling 736 patients were included in the meta-analysis. Compared with general oxygen therapy, NIV used immediately after planned extubation in patients with chronic respiratory disease reduced the reintubation rate (p=0.02), ventilator-associated pneumonia (VAP) incidence rate (p=0.000), and ICU mortality (p=0.002) and increased the level of PO2 (p=0.03).Conclusion: Non-invasive ventilation used immediately after planned extubation seems to be advantageous for decreasing the reintubation rate, VAP incidence, and ICU death rate in patients with chronic respiratory disease. %U https://smj.org.sa/content/smj/39/2/131.full.pdf