PT  - JOURNAL ARTICLE
AU  - Ou, Jinnan
AU  - Chen, Huaying
AU  - Li, Lezhi
AU  - Zhao, Liping
AU  - Nie, Na
TI  - The role of non-invasive ventilation used immediately after planned extubation for adults with chronic respiratory disorders
AID  - 10.15537/smj.2018.2.21942
DP  - 2018 Feb 01
TA  - Saudi Medical Journal
PG  - 131--136
VI  - 39
IP  - 2
4099  - http://smj.org.sa/content/39/2/131.short
4100  - http://smj.org.sa/content/39/2/131.full
SO  - Saudi Med J2018 Feb 01; 39
AB  - Objectives: To estimate the benefits of non-invasive ventilation (NIV) used immediately after planned postextubation in patients with chronic respiratory disorders.Methods: Cochrane Library, PubMed, the Chinese BioMedical Literature Database of clinical trials (CBD) and Embase were searched for pertinent studies by 2 trained investigators. Pooled odds ratios and 95% confidence intervals (CIs) were calculated by employing both fixed-effects and random-effects models.Results: Eight studies enrolling 736 patients were included in the meta-analysis. Compared with general oxygen therapy, NIV used immediately after planned extubation in patients with chronic respiratory disease reduced the reintubation rate (p=0.02), ventilator-associated pneumonia (VAP) incidence rate (p=0.000), and ICU mortality (p=0.002) and increased the level of PO2 (p=0.03).Conclusion: Non-invasive ventilation used immediately after planned extubation seems to be advantageous for decreasing the reintubation rate, VAP incidence, and ICU death rate in patients with chronic respiratory disease.