PT  - JOURNAL ARTICLE
AU  - Khan, Anas A.
TI  - Heat related illnesses
AID  - 10.15537/smj.2019.12.24727
DP  - 2019 Dec 01
TA  - Saudi Medical Journal
PG  - 1195--1201
VI  - 40
IP  - 12
4099  - http://smj.org.sa/content/40/12/1195.short
4100  - http://smj.org.sa/content/40/12/1195.full
SO  - Saudi Med J2019 Dec 01; 40
AB  - Climate change is the most challenging natural calamity of chronic nature that presents intense episodes of heat waves, and events. Effects of heat waves and increasing average temperature on heat-related illnesses (HRIs) demand a review of existing preventive and treatment strategies to direct future research. Heat-related illnesses are presented as minor to severe life-threatening conditions. Despite the understanding of the pathophysiology of HRI, pharmacological interventions are limited. Prevention is the best strategy against HRI. There is a dearth of epidemiological studies that reviewed the effect of pharmacological interventions on mortality, and there remains a need to identify critical key components other than inflammatory modulators, which can be targeted to decrease HRI.