RT Journal Article SR Electronic T1 The clinical outcome of HIV infection at a tertiary care center in Riyadh, Saudi Arabia JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 965 OP 970 DO 10.15537/smj.2020.9.25274 VO 41 IS 9 A1 Baadani, Abeer M. A1 Ballool, Sulafa A1 Alhemyadi, Salwa A1 Sallam, Lina A1 ALsufyani, Eid A1 Alghamdi, Alaa A1 Alfahad, Wafaa YR 2020 UL http://smj.org.sa/content/41/9/965.abstract AB Objectives: To investigate clinical characteristics and the outcome of people living with HIV (PLWHIV) at tertiary care center in Riyadh, Saudi Arabia.Methods: The present retrospective, observational study was carried between 2000-2019 at Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia. The demographic and clinical characteristics of 137 PLWHIV patients were collected by reviewing the medical data record.Results: Of the total 137 PLWHIV, 78.8% were male and 21.2% were female. At care entry, the most opportunistic infections found were the cytomegalovirus infections. cytomegalovirus (CMV) infections in 13.8% of patients, tuberculosis (8%), AIDS associated malignancy (10.9%), hepatitis B (5.8%), NTM (3.6%), hepatitis C (2.2%). In the present study, more than half of the patients received integrase based combination therapy. The highest number (n=20) of patients were diagnosed in 2018.Conclusions: Our findings describe the clinical characteristics and outcomes of PLWHIV at a major tertiary referral hospital in Saudi Arabia. The non AIDS related disease is the major cause of death in HIV infected patients. Early diagnosis and initiation of antiretroviral therapy resulted in a significant decrease in morbidity and mortality.