RT Journal Article
SR Electronic
T1 Regular intermittent bolus provides similar incidence of maternal fever compared with continuous infusion during epidural labor analgesia
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1237
OP 1242
VO 35
IS 10
A1 Feng, Shan-Wu
A1 Xu, Shi-Qin
A1 Ma, Li
A1 Li, Cai-Juan
A1 Wang, Xian
A1 Yuan, Hong-Mei
A1 Wang, Fu-Zhou
A1 Shen, Xiao-Feng
A1 Ding, Zheng-Nian
YR 2014
UL http://smj.org.sa/content/35/10/1237.abstract
AB OBJECTIVES: To compare the effects of regular intermittent bolus versus continuous infusion for epidural labor analgesia on maternal temperature and serum interleukin-6 (IL-6) level.METHODS: This randomized trial was performed in Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu Province, China between October 2012 and February 2014. Either regular intermittent bolus (RIB, n=66) or continuous infusion (CI, n=66) was used for epidural labor analgesia. A bolus dose (10 ml of 0.08% ropivacaine + 0.4 µg·ml-1 sufentanil) was manually administrated once an hour in the RIB group, whereas the same solution was continuously infused at a constant rate of 10 ml·h-1 in the CI group. Maternal tympanic temperature and serum IL-6 level were measured hourly from baseline to one hour post partum. The incidences of fever (>/=38 degree celsius ) were calculated.RESULTS: The incidence of maternal fever was similar between the 2 groups. There was a rising trend in mean temperature over time in both groups, but no statistical difference was detected between the groups at respective time points; maternal serum IL-6 showed similar changes.CONCLUSION: Compared with continuous infusion, regular intermittent bolus presents with the same incidence of maternal fever for epidural labor analgesia. Interleukin-6 elevation could be involved in mean maternal temperature increase.