RT Journal Article SR Electronic T1 Cause analysis and therapeutic methods of chylous leakage after pancreaticoduodenectomy JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1396 OP 1399 VO 35 IS 11 A1 Ji, Weiping A1 Wang, Juan A1 Song, Bin A1 Zheng, Kailian A1 Ma, Hongyun A1 Nadaf, Asaad A1 Shao, Zhuo A1 Jin, Gang YR 2014 UL http://smj.org.sa/content/35/11/1396.abstract AB OBJECTIVES: To study and analyze the causes of chylous leakage after pancreaticoduodenectomy.METHODS: We retrospectively analyzed 381 patients who underwent pancreaticoduodenectomy (including pylorus-preserving pancreaticoduodenectomy) in Shanghai Chang Hai Hospital Affiliated to the Second Military Medical University, Shanghai, China between January 2010 and December 2012. We also studied the relationship between postoperative chylous leakage and age, gender, surgical approach, and the tumor nature.RESULTS: The chylous leak was placed in 23 patients and the incidence of chylous leakage in patients was 0.6%. There was no significant difference in gender, age and tumor pathological pattern between the chylous leakage group and non-chylous leakage group. The incidence of chylous leakage in patients with N1 grade cancer was significantly higher than that in patients with N0 grade cancer (p=0.001). The incidence of chylous leakage in patients suffering R0 resection was significantly higher than that in patients suffering non-R0 resection (p=0.008). All patients were successfully treated conservatively.CONCLUSION: The incidence of chylous leakage was 0.6% and the chylous leakage was closely linked with the tumor’s grade malignancy and the range of radical resection.