PT  - JOURNAL ARTICLE
AU  - Bawazeer, Naif A.
AU  - Al-Jifree, Hatim M.
AU  - Gari, Abdulrahim M.
TI  - Malignant transformation of persistent endometriosis after hysterectomy
DP  - 2014 Nov 01
TA  - Saudi Medical Journal
PG  - 1390--1392
VI  - 35
IP  - 11
4099  - http://smj.org.sa/content/35/11/1390.short
4100  - http://smj.org.sa/content/35/11/1390.full
SO  - Saudi Med J2014 Nov 01; 35
AB  - The malignant transformation of persistent endometriotic implants into endometrioid adenocarcinoma is rare, especially after remote hysterectomy and salpingo-oophorectomy (TAH-BSO), and there are few cases reported in the English language literature. Patients receiving estrogen replacement therapy are common among the reported cases. We present a case that demonstrates the possibility of malignant transformation in a 53-year-old female, known case of endometriosis, who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy with no evidence of malignancy in the final pathology report. After 9 years, she presented with lower abdominal mass, and histopathological studies confirmed the diagnosis of well-differentiated endometrioid adenocarcinoma. The possibility of malignant transformation and possible risk factors are discussed with a brief literature review.