PT - JOURNAL ARTICLE AU - Koul, Roshan AU - Chacko, Alexander AU - Sankhla, Dilip K. TI - Corpus callosum agenesis DP - 2001 Jan 01 TA - Saudi Medical Journal PG - 22--25 VI - 22 IP - 1 4099 - http://smj.org.sa/content/22/1/22.short 4100 - http://smj.org.sa/content/22/1/22.full SO - Saudi Med J2001 Jan 01; 22 AB - OBJECTIVE: The objectives are to analyse corpus callosum agenesis in children with various neurological problems in a hospital set-up, and to study the neurological and systemic abnormalities associated with this condition.METHODS: The children with various neurological problems who underwent computerized tomography brain from January 1993 to December 1997, and were found to have corpus callosum agenesis, formed the subjects of this study. These children were examined for any syndromic association, congenital infections or metabolic defects.RESULTS: Out of 2164 children who underwent computerized tomography brain, 22 had corpus callosum agenesis (1%). Most cases were not syndromic and 64% were males. Epileptic disorders were noted in about one third of cases.CONCLUSION: Corpus callosum agenesis is an important anomaly in children with neurodevelopment handicaps, usually detected by neuroradiology.