PT  - JOURNAL ARTICLE
AU  - Abdul Salam, Mahmoud N.
AU  - Hasanain, Fathia H.
AU  - Greiew, Bothina K.
TI  - Hope for clomiphene citrate resistant ovaries
DP  - 2001 Jun 01
TA  - Saudi Medical Journal
PG  - 508--511
VI  - 22
IP  - 6
4099  - http://smj.org.sa/content/22/6/508.short
4100  - http://smj.org.sa/content/22/6/508.full
SO  - Saudi Med J2001 Jun 01; 22
AB  - OBJECTIVE: To assess the presentation, different surgical modalities and their outcome in the treatment of polycystic ovarian disease.METHODS: A retrospective study was carried out on 66 patients with polycystic ovarian disease. The majority of the cases had a history of infertility for at least 2 years and were known to be clomiphene citrate resistant in the Saudi German Hospital, Jeddah between 1994 and 1998 undergoing laparoscopic ovarian drilling.RESULTS: More than 80% of the patients were below 30 years of age. The majority of cases below 30 years had primary infertility. Irregular cycle was the main clinical presentation in 75% of cases; ovarian volume was more than 5.5cm3 in all of the cases. Diathermy drilling was carried out for 50 patients, laser for 12 patients and wedge resection for 4 patients. The follow-up treatment showed that pregnancy rate was 23%, 38% and 0% in the 3 groups. Cases that failed to conceive had significantly higher luteinizing hormone level.CONCLUSION: Laparoscopic ovarian drilling using diathermy or laser is effective during the induction of ovulation and increases the pregnancy rate in cases of polycystic ovarian disease resistant to clomiphene citrate.