PT  - JOURNAL ARTICLE
AU  - Haddad, Issa K.
TI  - Temporomandibular joint osteoarthrosis. Histopathological study of the effects of intra-articular injection of triamcinolone acetonide
DP  - 2000 Jul 01
TA  - Saudi Medical Journal
PG  - 675--679
VI  - 21
IP  - 7
4099  - http://smj.org.sa/content/21/7/675.short
4100  - http://smj.org.sa/content/21/7/675.full
SO  - Saudi Med J2000 Jul 01; 21
AB  - OBJECTIVE: The aim of this study was to investigate the histopathological changes of human temporomandibular joint osteoarthrosis following intra-articular injection of triamcinolone acetonide, and compare the results to these of control group.METHODS: One hundred and forty nine patients who complained of temporomandibular joint dysfunction underwent non-surgical treatment for at least 6 months. Twenty three patients had high condylectomy as a treatment. Forty four patients received two intra-articular injections of triamcinolone acetonide. Histological study was carried out on 44 specimens from 41 patients, the histological changes were recorded for each specimen.RESULTS: Patients who received temporomandibular intra-articular injection of triamcinolone acetonide showed damage to the fibrous layer (100%), to the cartilage (64%) and to the bone (42%). In those cases treated by condylectomy there were changes in the fibrous layer (100%), in the cartilaginous layer (68%) and to the bony layer (32%). Analysis of the results showed that the changes seen in the steroid (triamcinolone acetonide) group were more obvious than the changes in the non-steroid group.CONCLUSION: The result of this study indicated that intra-articular injection of steroid (triamcinolone acetonide) into human osteoarthritic temporomandibular joints acts as a lytic agent.