PT  - JOURNAL ARTICLE
AU  - Shihadeh, Awad S.
AU  - Nawafleh, Ashraf N.
TI  - The value of treating the male partner in vaginal candidiasis
DP  - 2000 Nov 01
TA  - Saudi Medical Journal
PG  - 1065--1067
VI  - 21
IP  - 11
4099  - http://smj.org.sa/content/21/11/1065.short
4100  - http://smj.org.sa/content/21/11/1065.full
SO  - Saudi Med J2000 Nov 01; 21
AB  - OBJECTIVE: To determine whether treatment of the sexual partners of women with vulvo-vaginal candidiasis with oral Ketoconazole can affect the cure and recurrence rate of candida vaginitis.METHODS: A total number of 144 women with vaginal candidiasis were treated with Ketoconazole 400 mg daily for 7 days, and half the male partners were treated with Ketoconazole 400 mg daily for 7 days. All women had physical follow-up examination, and mycological cultures were obtained at one week and four weeks after the start of treatment. The incidence of predisposing factors or of a recurrence history did not differ between treatment groups. Chi-square test was used to determine the significance of difference between the two groups with or without simultaneous treatment of the male partners.RESULTS: In the control group (untreated partners) 53 of 72 patients were cured after one week, with a cure rate of 74%, compared to 57 of 72 patients (treated partners) with a cure rate of 79%. The recurrence rate in the control group (untreated partners) 4 weeks after the start of treatment was 28 of 53 (53%), compared to 35 of 57 (61%) in the (untreated partners) group. No significant statistical difference was found in the cure and recurrence rates for both groups.CONCLUSION: Simultaneous treatment of the male partners with Ketoconazole did not influence either cure rate or recurrence rate in women with vaginal candidiasis.