RT Journal Article SR Electronic T1 Thyroiditis induced by interferon in dialysis JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 96 OP 98 VO 21 IS 1 A1 Ali S. Al-Harbi A1 Hatem Mansy A1 John Moloney YR 2000 UL http://smj.org.sa/content/21/1/96.abstract AB We describe a dialysis patient who acquired acute Hepatitis C infection. Her primary renal disease was systemic lupus erythromatosis. She was having goitre but clinically euthyroid and her thyroid function test was normal. To avoid long term complications of Hepatitis C we elected to treat her with Interferon 3 million units subcutaneously 3 times a week. During treatment she developed some transient side effects initially which subsided but later she felt pressure symptoms around her neck. When we checked her TSH and thyroid antibodies these were elevated. Though this could be related to HCV, rarely, but we think the thyroid change is mostly related to Interferon. Some possible explanation of the effect of Interferon on thyroid have been reviewed and we think patients getting such drugs should be under close monitoring to avoid permanent thyroid dysfunction.