PT  - JOURNAL ARTICLE
AU  - Yasseen, Akeel A.
AU  - Al-Khafaji, Salih M.
TI  - The role of Y chromosome C- band size polymorphism in male infertility with a reference to their effect on the total length of the chromosome
DP  - 2004 Apr 01
TA  - Saudi Medical Journal
PG  - 452--455
VI  - 25
IP  - 4
4099  - http://smj.org.sa/content/25/4/452.short
4100  - http://smj.org.sa/content/25/4/452.full
SO  - Saudi Med J2004 Apr 01; 25
AB  - OBJECTIVE: To assess the contribution of chromosome on sperm production.METHODS: During a 2 year period from October 1999 to December 2001 a total of 200 male patients were included in the present study. The study was carried out at Kufa Medical College, Kufa, Iraq. Blood culture, chromosomal harvesting, Giemsa stain, C-band technique and C-band size calculation have been conducted according to the standard methods.RESULTS: No statistical differences have been recorded in the C-band size distribution level among the infertile groups compared to normal control. The functional relationship between C-band, euchromatin and the total length of the Y chromosome showed a strong correlation coefficient among the infertile groups (oligospermia, azoospermia) as well as the normal control.CONCLUSION: In our qualitative study the C-band size of the Y chromosome has no effect on spermatogenesis. The decrease in the size of Y chromosome is due to the decrease in both the heterochromatin and euchromatin regions.