RT Journal Article
SR Electronic
T1 The role of Y chromosome C- band size polymorphism in male infertility with a reference to their effect on the total length of the chromosome
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 452
OP 455
VO 25
IS 4
A1 Yasseen, Akeel A.
A1 Al-Khafaji, Salih M.
YR 2004
UL http://smj.org.sa/content/25/4/452.abstract
AB OBJECTIVE: To assess the contribution of chromosome on sperm production.METHODS: During a 2 year period from October 1999 to December 2001 a total of 200 male patients were included in the present study. The study was carried out at Kufa Medical College, Kufa, Iraq. Blood culture, chromosomal harvesting, Giemsa stain, C-band technique and C-band size calculation have been conducted according to the standard methods.RESULTS: No statistical differences have been recorded in the C-band size distribution level among the infertile groups compared to normal control. The functional relationship between C-band, euchromatin and the total length of the Y chromosome showed a strong correlation coefficient among the infertile groups (oligospermia, azoospermia) as well as the normal control.CONCLUSION: In our qualitative study the C-band size of the Y chromosome has no effect on spermatogenesis. The decrease in the size of Y chromosome is due to the decrease in both the heterochromatin and euchromatin regions.