PT  - JOURNAL ARTICLE
AU  - Al-Hamad, Nadia M.
AU  - Al-Eisa, Amal A.
TI  - Renal abnormalities in congenital chloride diarrhea
DP  - 2004 May 01
TA  - Saudi Medical Journal
PG  - 651--655
VI  - 25
IP  - 5
4099  - http://smj.org.sa/content/25/5/651.short
4100  - http://smj.org.sa/content/25/5/651.full
SO  - Saudi Med J2004 May 01; 25
AB  - Congenital chloride diarrhea CLD is a rare autosomal recessive disorder caused by a defect in the chloride/ bicarbonate exchange in the ileum and colon. It is characterized by watery diarrhea, abdominal distension, hypochloremic hypokalemic metabolic alkalosis with high fecal content of chloride >90 mmol/l. We report 3 patients with CLD associated with various renal abnormalities including chronic renal failure secondary to renal hypoplasia, nephrocalcinosis and congenital nephrotic syndrome.