RT Journal Article
SR Electronic
T1 Renal abnormalities in congenital chloride diarrhea
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 651
OP 655
VO 25
IS 5
A1 Al-Hamad, Nadia M.
A1 Al-Eisa, Amal A.
YR 2004
UL http://smj.org.sa/content/25/5/651.abstract
AB Congenital chloride diarrhea CLD is a rare autosomal recessive disorder caused by a defect in the chloride/ bicarbonate exchange in the ileum and colon. It is characterized by watery diarrhea, abdominal distension, hypochloremic hypokalemic metabolic alkalosis with high fecal content of chloride >90 mmol/l. We report 3 patients with CLD associated with various renal abnormalities including chronic renal failure secondary to renal hypoplasia, nephrocalcinosis and congenital nephrotic syndrome.