PT  - JOURNAL ARTICLE
AU  - Haouimi, Ammar S.
AU  - Al-Hawsawi, Zakaria M.
AU  - Jameel, Ahmed N.
TI  - Unusual location of eosinophilic granuloma
DP  - 2004 Oct 01
TA  - Saudi Medical Journal
PG  - 1489--1491
VI  - 25
IP  - 10
4099  - http://smj.org.sa/content/25/10/1489.short
4100  - http://smj.org.sa/content/25/10/1489.full
SO  - Saudi Med J2004 Oct 01; 25
AB  - Eosinophilic granuloma EG is a benign self-limiting disease, which belongs to the spectrum of Langerhans' cell histiocytosis LCH. The etiology of LCH remains unknown, although the evidence indicates that it is a clonal proliferative disorder of Langerhans cells, it has also been characterized as reactive disorder, neoplastic process and a berrant immune response. Eosinophilic granuloma is characterized by single or multiple skeletal lesions occurring predominately in children, adolescents and young adults, it accounts for 70% of LCH. It is more common in males, and the common sites are the skull, mandible, ribs, spines and long bones particularly the femur and the humerus. The estimated incidence of EG is 3-4 per million of the population. Vertebral bone involvement is rarely seen and usually affects the vertebral body. We are reporting an unusual case of EG in a female child presented with a solitary lesion at posterior element of lumbar vertebra.