TY - JOUR T1 - Innovations in pancreas transplantation JF - Saudi Medical Journal JO - Saudi Med J SP - 265 LP - 271 VL - 23 IS - 3 AU - Haider A. Al-Shurafa AU - Muaffak T. Jawdat AU - Atef F. Bassas AU - Xavier C. Rogiers AU - Wolf O. Bechstein Y1 - 2002/03/01 UR - http://smj.org.sa/content/23/3/265.abstract N2 - Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment. ER -