RT Journal Article
SR Electronic
T1 Innovations in pancreas transplantation
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 265
OP 271
VO 23
IS 3
A1 Al-Shurafa, Haider A.
A1 Jawdat, Muaffak T.
A1 Bassas, Atef F.
A1 Rogiers, Xavier C.
A1 Bechstein, Wolf O.
YR 2002
UL http://smj.org.sa/content/23/3/265.abstract
AB Pancreas transplantation is currently the curative treatment for type 1 diabetes mellitus. It aims at providing physiological insulin replacement therapy in type 1 diabetes mellitus. The goal is thereby also to prevent secondary complications of diabetes. Long term control of glucose metabolism has only been achieved by pancreas transplantation. As a result of improvements in the surgical techniques and the efficacy of immunosuppression, the patient and graft survival rates have improved dramatically over the last 2 decades. As a result, pancreas transplantation, as part of simultaneous pancreas and kidney transplantation, pancreas after kidney transplantation, and exceptionally pancreas transplantation alone, became the standard therapeutic option for patients with type 1 diabetes mellitus with end-stage renal disease. In this article we review the pancreas transplantation methods, indications, techniques, and the short as well as the long outcomes of treatment.