PT - JOURNAL ARTICLE AU - Ezzeldin, Kamal M. AU - Ezzeldin, Asmaa A. AU - Zahrani, Ahmad J. AU - Al-Zaiem, Maher M. TI - Precocious puberty in a female with Proteus Syndrome DP - 2002 Mar 01 TA - Saudi Medical Journal PG - 332--334 VI - 23 IP - 3 4099 - http://smj.org.sa/content/23/3/332.short 4100 - http://smj.org.sa/content/23/3/332.full SO - Saudi Med J2002 Mar 01; 23 AB - Proteus syndrome is a complex disorder comprising malformations and overgrowth of multiple tissues and characterized by its polymorphism and mosaicism. The syndrome is rare and sporadic. Oliveira M da C et al1 reported the first case of Proteus syndrome associated with precocious puberty in a boy. We are reporting a case of a 7-month old girl with Proteus syndrome who developed a juvenile granulosa cell tumor in one ovary causing precocious puberty. At our knowledge this is the first case of Proteus syndrome with precocious puberty in a female.