RT Journal Article
SR Electronic
T1 Precocious puberty in a female with Proteus Syndrome
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 332
OP 334
VO 23
IS 3
A1 Kamal M. Ezzeldin
A1 Asmaa A. Ezzeldin
A1 Ahmad J. Zahrani
A1 Maher M. Al-Zaiem
YR 2002
UL http://smj.org.sa/content/23/3/332.abstract
AB Proteus syndrome is a complex disorder comprising malformations and overgrowth of multiple tissues and characterized by its polymorphism and mosaicism. The syndrome is rare and sporadic. Oliveira M da C et al1 reported the first case of Proteus syndrome associated with precocious puberty in a boy. We are reporting a case of a 7-month old girl with Proteus syndrome who developed a juvenile granulosa cell tumor in one ovary causing precocious puberty. At our knowledge this is the first case of Proteus syndrome with precocious puberty in a female.