PT  - JOURNAL ARTICLE
AU  - Tariq Y. Khashoggi
TI  - Outcome of pregnancies with preterm premature rupture of membranes
DP  - 2004 Dec 01
TA  - Saudi Medical Journal
PG  - 1957--1961
VI  - 25
IP  - 12
4099  - http://smj.org.sa/content/25/12/1957.short
4100  - http://smj.org.sa/content/25/12/1957.full
SO  - Saudi Med J2004 Dec 01; 25
AB  - OBJECTIVE: To study the outcomes of pregnancies complicated with preterm premature rupture of the membranes (PPROM) between 26-36 week gestation.METHODS: A retrospective study of 36670 pregnancies registered and managed in the Department of Obstetrics and Gynecology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia (KSA) from March 1993 to February 2003.RESULTS: Two hundred and twenty cases of PPROM (0.6%) were registered and treated expectantly out of 36670 total pregnancies registered during the study period. The majority of the cases (38.6%) were delivered within 72 hours of premature rupture of the membranes (PROM). Only 2.3% of the cases were prolonged to a latency period of more than one month. Maternal morbidity included chorioamnionitis (20.9%), postpartum endometritis (6.8%), abruptio placentae (4%) and septicemia (0.5%). The prenatal survival rate was 94.5% whereas neonatal outcomes included neonatal mortality (5.5%), respiratory distress (15.9%), sepsis (7.7%), and necrotizing enterocolitis (3.1%). Our study showed a positive correlation between increasing maternal age and cesarean section; increased maternal and neonatal infection rates with prolonged latency; and increased risk of neonatal infection among mothers having chorioamnionitis.CONCLUSION: The incidence of PPROM in KSA is low. Ultimate goal of therapy must be safety of the mother first. Expectant management should be the rationale if fetal immaturity exists. Induction of labor in PPROM patient >/= 34-week-gestation is a logical approach to minimize maternal infectious morbidity.