PT  - JOURNAL ARTICLE
AU  - Bukhary, Zakeya
AU  - Mahmood, Wafeeq
AU  - Al-Khani, Ahmed
AU  - Al-Abdely, Hail M.
TI  - Treatment of nosocomial meningitis due to a multidrug resistant Acinetobacter baumannii with intraventricular colistin
DP  - 2005 Apr 01
TA  - Saudi Medical Journal
PG  - 656--658
VI  - 26
IP  - 4
4099  - http://smj.org.sa/content/26/4/656.short
4100  - http://smj.org.sa/content/26/4/656.full
SO  - Saudi Med J2005 Apr 01; 26
AB  - We report a case of serious nosocomial meningitis due to a multidrug-resistant Acinetobacter baumannii in a 23-year-old woman who had a posterior fossa craniotomy with upper cervical laminectomy for excision of a meningioma at the level of foramen magnum. Post-operatively, she had neck pain with continuous fever and deterioration in the level of consciousness and convulsions. The CSF was turbid and had neutrophil pleocytosis. A multidrug-resistant Acinetobacter baumannii was isolated from the blood and CSF. The patient failed high doses of imipenem, ciprofloxacin and systemic colistin but responded well to intraventricular injections of colistin 125,000 units twice daily for 3 weeks. No apparent side effects were noticed. We have reviewed other similar cases reported in the literature.