RT Journal Article
SR Electronic
T1 Treatment of nosocomial meningitis due to a multidrug resistant Acinetobacter baumannii with intraventricular colistin
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 656
OP 658
VO 26
IS 4
A1 Bukhary, Zakeya
A1 Mahmood, Wafeeq
A1 Al-Khani, Ahmed
A1 Al-Abdely, Hail M.
YR 2005
UL http://smj.org.sa/content/26/4/656.abstract
AB We report a case of serious nosocomial meningitis due to a multidrug-resistant Acinetobacter baumannii in a 23-year-old woman who had a posterior fossa craniotomy with upper cervical laminectomy for excision of a meningioma at the level of foramen magnum. Post-operatively, she had neck pain with continuous fever and deterioration in the level of consciousness and convulsions. The CSF was turbid and had neutrophil pleocytosis. A multidrug-resistant Acinetobacter baumannii was isolated from the blood and CSF. The patient failed high doses of imipenem, ciprofloxacin and systemic colistin but responded well to intraventricular injections of colistin 125,000 units twice daily for 3 weeks. No apparent side effects were noticed. We have reviewed other similar cases reported in the literature.