RT Journal Article
SR Electronic
T1 Acute chest syndrome
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1037
OP 1044
VO 23
IS 9
A1 Al-Dabbous, Ibrahim A.
YR 2002
UL http://smj.org.sa/content/23/9/1037.abstract
AB Acute chest syndrome is an acute pulmonary illness in patients with sickle cell disease. It is a common problem, causing significant morbidity and mortality. Many factors may cause this syndrome. Treatment is primarily supportive. Therapy includes hydration, analgesia, supplemental oxygen, antibiotics, blood transfusion and mechanical ventilation. Early detection and aggressive management may limit its severity and prevent its complications. This article reviews the current information for its definition, frequency, pathogenesis, clinical features, complications, investigations, management and prevention. Recent advances in management of acute and recurrent attacks will be discussed.