RT Journal Article
SR Electronic
T1 Localized extramedullary relapse after autologous hematopoietic stem cell transplantation in multiple myeloma
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 989
OP 991
VO 26
IS 6
A1 Erkus, Muhan
A1 Bolaman, Zahit
A1 Meteoglu, Ibrahim
A1 Kadikoylu, Gurhan
YR 2005
UL http://smj.org.sa/content/26/6/989.abstract
AB Extramedullary plasmacytomas are rare manifestation of plasma cell malignancies. After hematopoietic stem cell transplantation HSCT, presentation of localized plasmacytoma with extramedullary growth is very unusual. We report a case of a 56-year-old woman with Dune-Salmon stage IIIA immunoglobulin A-kappa multiple myeloma, which presented 120 days after autologous HSCT with extramedullary plasmacytoma arising from a lymph node in supraclavicular region. The patient had no pretransplant-history related with extramedullary disease. There was no increase of plasma cells in bone marrow or monoclonal protein in urine or serum. Aspiration smears of lymph node revealed a population of plasmacytoid cells at various stages of maturation. The patient was successfully treated with local radiotherapy and has remained progression-free for more than 20 months.