@article {Khaled23, author = {Boumediene M. Khaled and Malika Bendahmane and Slimane Belbraouet}, title = {Ramadan fasting induces modifications of certain serum components in obese women with type 2 diabetes}, volume = {27}, number = {1}, pages = {23--26}, year = {2006}, publisher = {Saudi Medical Journal}, abstract = {OBJECTIVE: To examine the effect of fasting during Ramadan on certain serum components such as fasting serum glucose (FSG), glycated hemoglobin (HbA1c), total cholesterol (TC), triglycerides (TGs), high density lipoproteins (HDL-C), and low density lipoproteins (LDL-C) parameters in obese women patients with type 2 diabetes.METHODS: We conducted the study in Petit-Vichy Diabetology Center, Sidi-Bel-Abbes, Algeria from October 2003 to March 2004, on 60 obese outpatient women (BMI = 35.41 {\textpm} 3.64~kg/m2), aged 51 {\textpm} 10~years, who had diabetes for 5 {\textpm} 2.5~years. The patients followed no specific diet, on medications, and presenting no degenerative complications. We carried out the study over 3 periods: before (pre-fasting), during (fasting), and after Ramadan month (post-fasting).RESULTS: Comparing Ramadan (fasting period) with non-Ramadan days (pre- and post-fasting periods), we observed significant decreases in FSG (16.72\%, p\<0.001), in HbA1c (11.3\%, p\<0.005), and in HDL-C (26.81\%, p\<0.001) rates, while TC (13.85\%, p\<0.001), TGs (16.9\%, p\<0.003), and the LDL-C (22.39\%, p\<0.0001) levels increased significantly.CONCLUSION: These findings show a beneficial effect of fasting during Ramadan on glucose homeostasis, however, we observed an unbalanced profile on lipids.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/27/1/23}, eprint = {https://smj.org.sa/content/27/1/23.full.pdf}, journal = {Saudi Medical Journal} }