PT  - JOURNAL ARTICLE
AU  - Aziz, Khalil A.
TI  - Elucidation of the mechanisms of hairy-cell localization in tissues and the process of the bone marrow fibrosis in hairy-cell leukemia
DP  - 2003 Jul 01
TA  - Saudi Medical Journal
PG  - 715--719
VI  - 24
IP  - 7
4099  - http://smj.org.sa/content/24/7/715.short
4100  - http://smj.org.sa/content/24/7/715.full
SO  - Saudi Med J2003 Jul 01; 24
AB  - Hairy cell leukemia is a chronic B cell leukemia with a number of distinctive features including the unusual tissue distribution of the leukemic cells, hairy cells, and the bone marrow fibrosis. We have been working, for a number of years, on the potential mechanisms behind hairy-cell localization in tissues. In this review, it is summarized how our work has shed very important information regarding these mechanisms and led, eventually, to the full elucidation of the process of the bone marrow fibrosis in hairy cell leukemia.