@article {Wang1151, author = {Hui-Bo Wang and Jun Yang}, title = {The role of renin-angiotensin aldosterone system related micro-ribonucleic acids in hypertension}, volume = {36}, number = {10}, pages = {1151--1155}, year = {2015}, doi = {10.15537/smj.2015.10.12458}, publisher = {Saudi Medical Journal}, abstract = {Micro-ribonucleic acids (miRNAs) are small (21-25 nucleotide) single-stranded, evolutionarily conserved non-protein-coding RNAs, which control diverse cellular functions by interacting with the 3{\textquoteright} untranslated region of specific target messenger RNAs at the post-transcriptional level. Research shows that an aberrant expression profile of miRNAs has been linked to a series of diseases, including hypertension. In the past few decades, it has been demonstrated that excessive activation of the renin-angiotensin aldosterone system (RAAS) involves in the pathogenesis of hypertension. This article reviews the latest insights in the identification of RAAS-correlative miRNAs and the potential mechanisms for their roles in hypertension.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/36/10/1151}, eprint = {https://smj.org.sa/content/36/10/1151.full.pdf}, journal = {Saudi Medical Journal} }