PT - JOURNAL ARTICLE AU - Elnahas, Amir AU - Gerais, Abd S. AU - Elbashir, Mustafa I. AU - Eldien, Eltoum S. AU - Adam, Ishag TI - Toxoplasmosis in pregnant Sudanese women DP - 2003 Aug 01 TA - Saudi Medical Journal PG - 868--870 VI - 24 IP - 8 4099 - http://smj.org.sa/content/24/8/868.short 4100 - http://smj.org.sa/content/24/8/868.full SO - Saudi Med J2003 Aug 01; 24 AB - OBJECTIVE: The aim of this study was to conduct a sero-epidemiological survey of toxoplasmosis in pregnant Sudanese women.METHODS: Four hundred and eighty-seven pregnant women attending antenatal clinics in Khartoum and Omdurman, Maternity Hospitals, Sudan during the period June through to December 2000 were counselled for socio-demographic and obstetrical risk factors for toxoplasmosis, and screened for immunoglobin G (IgG) and IgM anti-toxoplasma antibodies using enzyme linked immunoassay.RESULTS: Immunoglobin G anti-toxoplasma antibodies were positive (titre > 11 IU/ml) in 166/487 (34.1%), while 321/487(65.9%) were sero-negative. The sera of 35 women showed very high titres (>100 IU/ml), 5/35 (14.3%) were IgM-positive. The risk factors for IgG anti-toxoplasma seropositivity were; Southern ethnic origin and consumption of raw meat. Thirty (18.1%) out of 166 women who were IgG anti-toxoplasma seropositive gave history of intrauterine fetal death, while 31 (9.7%) out of 321 women who were sero-negative gave history of intrauterine fetal death, the difference was statistically significant (P < 0.05).CONCLUSION: Over 65% Sudanese women screened for anti-toxoplasma IgG antibodies were sero-negative and they were at risk of sero-conversion during pregnancy. Southers and eating raw meat were the risk factors for toxoplasmosis in Sudanese pregnant women.