PT - JOURNAL ARTICLE AU - Saxena, Shiv K. AU - Bin Salih, Salih A. AU - Al-Jizeeri, Ahmed H. AU - Kheir, Osman A. TI - Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome DP - 2003 Sep 01 TA - Saudi Medical Journal PG - 1013--1015 VI - 24 IP - 9 4099 - http://smj.org.sa/content/24/9/1013.short 4100 - http://smj.org.sa/content/24/9/1013.full SO - Saudi Med J2003 Sep 01; 24 AB - Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other autoimmune, infectious or neoplastic disorders. In this paper we report a 29-year-old Saudi female, a known case of antiphospholipid syndrome, presented with complaints of fever, breathlessness and generalized fatigue. Further investigations confirmed her as a case of myeloblastic leukemia (M1, French-American-British classification). Acute myeloblastic leukemia is not described to be associated with primary antiphospholipid syndrome in the literature to date. This is the first case report of such association.