Table 1

- Effect of pioglitazone (PIO), caffeine (CAF), and PIO + CAF on blood sugar level.

GroupsDay 0 (mg/dl)Day 7 (mg/dl)Day 14 (mg/dl)
Normal rats80.67±2.89477.17±3.72881.33±4.143
Diabetic rats389.2±9.061400.3±6.854*405.5±7.628*
DIA+PIO397.0±8.278140.2±4.385[64.7%]131.8±2.880[66.8%]
DIA+CAF401.8±7.583250.8±6.096[37.6%]225.3±6.296[43.9%]
DIA+PIO+CAF392.7±5.760129.3±2.679[67.1%]122.2±5.167[68.9%]
  • Each value represents mean ± standard error of mean, for n=6. Values in parentheses indicates percentage reduction in glycemia.

  • p<0.001 compared to diabetic control.

  • * p<0.001 compared to normal control group. DIA: diabetic rats