Table 2

- Effect of pioglitazone (PIO), caffeine (CAF), and PIO + CAF on liver and cardiac biomarkers.

Groups	ALT (IU/L)	AST (IU/L)	LDH (IU/L)	CKMB (IU/L)
Normal rats	79.2±4.43	89.50±9.532	1223±18.78	538.7±10.07
Diabetic rats	231±6.56^{^§}	248.3±10.35^{^§}	1891±26.40^{^§}	1085±24.04^{^§}
DIA+PIO	136±9.01^{^†}[41.1%]	162.7±10.83^{^†}[34.5%]	1357±35.89^{^†}[28.2%]	752.0±11.95^{^†}[30.7%]
DIA+CAF	163±13.6^{^†}[29.4%]	196.0±10.19^**[21.1%]	1743±24.80^**[7.8%]	938.8±15.99^{^†}[13.5%]
DIA+PIO+CAF	96.3±8.58^{^†}[58.3%]	146.7±7.168^{^†}[40.9%]	1228±19.40^{^†}[35.1%]	632.8±13.51^{^†}[41.7%]

Each value represents mean ± standard error of mean, for n=6. Values in parentheses indicates percentage reduction.
↵** p<0.01;
↵^† p<0.001 compared to diabetic control group.
↵^§ p<0.001 compared to normal control group, DIA - diabetic rats