- Endothelial dysfunction and oxidative stress markers in the studied groups.
| Variables | Rheumatoid arthritis patients N=100 | Control N=50 | Test of significance | P-value | |
|---|---|---|---|---|---|
| VCAM-1 (pg/ml) | 1258.1 ± 386.3 | 759.9 ± 169.2 | 8.6 | <0.001 | |
| Total antioxidant capacity (mM/L) | 1.2 ± 0.1 | 1.3 ± 0.1 | 1.9 | 0.05 | |
| MDA (nmol/ml) | 6.5 ± 3.5 | 4.08 ± 2.5 | 4.3 | <0.001 | |
| Group 1 N=50 | Group 2 N=50 | Control N=50 | |||
| VCAM-1 (pg/ml) | Mean ± SD 1022.1 ± 200.1 | Mean ± SD 1494.1 ± 384.5 | Mean ± SD 75 9.9 ± 169.2 | 95.8 | <0.001 |
| P1<0.001, P2<0.001, P3<0.001 | |||||
| Total antioxidant capacity (mM/L) | 1.3 ± 0.1 | 1.1 ± 0.2 | 1.3 ± 0.1 | 13.0 | <0.001 |
| P1<0.001, P2=0.832, P3<0.001 | |||||
| MDA (nmol/ml) | 5.6 ± 3.7 | 7.3 ± 3.1 | 4.08 ± 2.5 | 13.2 | <0.001 |
| P1=0.025, P2=0.035, P3<0.001 | |||||
| Data are expressed as mean ± SD. VCAM-1: vascular cell adhesion molecule-1. MDA: malondialdehyde.P1: Group I vs II, P2: Group I vs III, P3: Group II vs III. P≤0.05 is significant. P<0.001 is highly significant. | |||||