- Hematological characteristics in patients with and without IDA with positive and negative Helicobacter pylori (H. pylori)infection, compared to the controls.
| IDA Study group (n=79) | Control group (n=30) | |||||
|---|---|---|---|---|---|---|
| Parameter of the hematology indexes | Positive H. pylori with IDA (n=49) | Negative H. pylori without IDA (n=30) | P-value | Positive H. pylori (n=7) | Negative H. p[ylori (n=23) | P-value |
| Gender, male/female | 18/31 | 13/17 | 0.01 | 4/3 | 14/9 | 0.4 |
| Age (years) | 45.16 ± 8.56 | 43.26 ± 11.23 | 0.39 | 41.63 ± 10.76 | 39.93 ± 11.26 | 0.29 |
| RBC (4.2-5.1 × 106/μL) | 3.74 ± 0.34 | 3.86 ± 0.37 | 0.14 | 4.62 ± 0.35 | 4.87 ± 0.42 | <0.0001 |
| Hemoglobin (12–15 g/dL) | 9.4 ± 1.62 | 9.8 ± 1.51 | 0.28 | 13.32 ± 0.76 | 14.28 ± 0.89 | <0.0001 |
| HCT (36-52%) | 33.1 ± 3.3 | 33.5 ± 3.6 | 0.61 | 40.49 ± 2.36 | 41.2 ± 2.82 | <0.0001 |
| MCV (80-98 ft) | 72.81 ± 5.98 | 73.34 ± 4.79 | 0.68 | 86.15 ± 2.19 | 87.31 ± 3.14 | <0.0001 |
| MCH (28-34 pg) | 22.79 ± 2.81 | 23.34 ± 1.20 | 0.31 | 28.71 ± 0.9 | 29.72 ± 1.71 | <0.0001 |
| Serum iron (40-165 μg/dL) | 26.2 ± 8.2 | 27.4 ± 11.6 | 0.56 | 74.67± 22.62 | 77.89 ± 21.98 | <0.0001 |
| Ferritin (13-280 ng/dL) | 7.1 ± 2.7 | 7.6 ± 3.6 | 0.48 | 66.2 ± 49.81 | 90.2 ± 52.96 | <0.0001 |
There were no statistically significant differences between patients with or without H. pylori infections among IDA patients. However, there was a markedly significant difference between H. pylori-positive patients and the control group in terms of the hematological parameters (p<0.0001). Values are presented as mean ± SD. SD: standard deviation, IDA: iron deficiency anemia, RBC: red blood cell count, HCT: hematocrit, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration