Table 4

- Possible causes and management of low O2 saturation on extracorporeal membrane oxygenation (ECMO).

ECMO blood flow ECMO blood flow (RPMs)Look for cause
Hemoglobin Hemoglobin (transfusion)Look for bleeding
Inadequate FiO2 or ventilator support FiO2 on ECMO Ventilator supportLook for cause
Too much flow through shunts or bridges (such as, contentious renal replacement therapy)Check and reduce shunt flow 
Oxygenator failureCheck pre- and post-oxygenator blood gasesIf yes change
PneumothoraxChest x-ray