- Sub analysis of estrogen receptor (ER) negative tumors with respect to age, tumor size, tumor grade, lymphovascular invasion, lymph node metastasis, distant metastasis and Ki67 expression.
| Variables | ≤40 with ER-ve (n=74) | >40 with ER-ve (n=145) | P value |
|---|---|---|---|
| Tumor size | 0.413 | ||
| ≤2 cm | 12 (16.2) | 31 (21.4) | |
| >2 cm - ≤5 cm | 55 (74.3) | 95 (65.5) | |
| >5 cm | 7 (9.5) | 19 (13.1) | |
| Histological grading | 0.341 | ||
| Grade I | 3 (4.0) | 4 (2.7) | |
| Grade II | 19 (25.7) | 51 (35.2) | |
| Grade III | 52 (70.3) | 90 (62.1) | |
| Axillary lymph node metastasis | 0.021 | ||
| No | 18 (24.3) | 57 (39.3) | |
| Yes | 56 (75.7) | 87 (60.7) | |
| Lymphovascular invasion | 0.575 | ||
| No | 12 (16.2) | 28 (19.3) | |
| Yes | 62 (83.8) | 117 (80.7) | |
| Distant metastases | 0.890 | ||
| No | 19 (25.7) | 36 (24.8) | |
| Yes | 55 (74.3) | 109 (75.2) | |
| Ki67 expression | <0.0001 | ||
| Negative | 0 (0) | 37 (25.5) | |
| Positive | 74 (100) | 108 (74.5) | |
Values are expressed as number and percentage (%)