Table 2

- Association of measles complications with SNPs in the TLR2 gene.

Measles complicationsSNPsTotal
rs3804099 allelers3804100 allelers1816702 allele
T>TC>TP-valueT>TC>TP-valueT>TC>TP-value
n (%)n (%)n (%)n (%)
Pneumonia8 (40)12 (60)0.11*13 (65)7 (35)0.765 (25)15 (75)0.1320 (40)
LRTI3 (37.5)5 (62.5)0.25*1 (12.5)7 (87.5)0.0041 (12.5)7 (87.5)0.128 (16)
Diarrhea4 (100)0 (0)0.123 (75)1 (25)0.644 (100)0 (0)0.024 (8)
Pneumonia + diarrhea2 (66.7)1 (33.3)1.02 (66.7)1 (33.3)1.00 (0)3 (100)0.263 (6)
Diarrhea + LRTI7 (87.5)1 (12.5)0.065 (62.5)3 (37.5)1.06 (75)2 (25)0.048 (16)
Pneumonia + otitis media2 (66.7)1 (33.3)1.03 (100)0 (0)0.262 (66.7)1 (33.3)0.553 (6)
Myocarditis + LRTI1 (100)0 (0)1.01 (100)0 (0)1.01 (100)0 (0)0.41 (2)
SSPE1 (100)0 (0)1.01 (100)0 (0)1.00 (0)1 (100)1.01 (2)
Pneumothorax0 (0)1 (100)0.41 (100)0 (0)1.00 (0)1 (100)1.01 (2)
Otitis media0 (0)1 (100)0.40 (0)1 (100)0.41 (100)0 (0)0.41 (2)
Total28 (56)22 (44) 30 (60)20 (40) 20 (40)30 (60) 50 (100)
  • LRTI: lower respiratory tract infection, SSPE: subacute sclerosing panencephalitis, SNPs: single nucleotide polymorphisms, TLR2: toll-like receptor -2, p<0.05 was considered significant at the 95% confidence interval (CI)

  • * Chi-square test,

  • Fisher’s exact test