- Synonymous and non-synonymous polymorphisms in the TLR2 gene.
| Polymorphism | Regulatory region | Coding region | |||
|---|---|---|---|---|---|
| rs1816702 | rs3804099 | rs3804100 | T513A† | L603M† | |
| Nucleotide position | 153,703,504 | 153,704,257 | 153,704,444 | 153,704,714 | |
| Amino acid position | 199 | 450 | 513 | 603 | |
| Codon wild type | AAT | AGT | ACG | CTG | |
| Codon mutant type | AAC | AGC | GCG | ATG | |
| Amino acid wild type | Asx | Ser | Thr | Leu | |
| Amino acid mutant type | Asx | Ser | Ala | Met | |
| Type of SNP | S | S | S | NS | NS |
TLR2: toll-like receptor -2, SNP: single nucleotide polymorphism, S: synonymous, NS: non-synonymous, †novel polymorphism