- Chemotherapy schedules for symptomatic infant neuroblastoma (4S).
| Cycles # | Chemotherapy Agents | Dosage | Day of treatment |
|---|---|---|---|
| 1 and 7 | Carboplatin | 18.6 mg/kg/dose ≤ 12 kg or 560 mg/m²/dose > 12 kg | Day 1 |
| Etoposide | 4 mg/kg/dose ≤ 12 kg or 120 mg/m2/dose > 12 kg | Days 1-3 | |
| 2 and 6 | Carboplatin | 18.6 mg/kg/dose ≤ 12 kg or 560 mg/m²/dose > 12 kg | Day 1 |
| Cyclophosphamide | 33.3 mg/kg/dose for patients ≤ 12 kg or 1000 mg/m2/dose for patients > 12 kg | Day 1 | |
| Doxorubicin | 1 mg/kg/dose for patients ≤ 12 kg or 30 mg/m2/dose for patients > 12 kg | Day 1 | |
| 3 and 5 | Cyclophosphamide | 33.3 mg/kg/dose for patients ≤ 12 kg or 1000 mg/m2/dose for patients > 12 kg | Day 1 |
| Etoposide | 4 mg/kg/dose ≤ 12 kg or 120 mg/m2/dose > 12 kg | Days 1-3 | |
| 4 | Carboplatin | 18.6 mg/kg/dose ≤ 12 kg or 560 mg/m²/dose > 12 kg | Day 1 |
| Etoposide | 4 mg/kg/dose ≤ 12 kg or 120 mg/m2/dose > 12 kg | Days 1-3 | |
| Doxorubicin | 1 mg/kg/dose for patients ≤ 12 kg or 30 mg/m2/dose for patients > 12 kg | Day 1 | |
| 8 | Cyclophosphamide | 33.3 mg/kg/dose for patients ≤ 12 kg or 1000 mg/m2/dose for patients > 12 kg | Day 1 |
| Doxorubicin | 1 mg/kg/dose for patients ≤ 12 kg or 30 mg/m2/dose for patients > 12 kg | Day 1 |