| PICOTS component | Details |
|---|---|
| Participants | Patients with COVID-19 suspected symptoms or asymptomatic population screening |
| Interventions | Saliva specimens RT-qPCR results of detect SARS-CoV-2 |
| Comparisons | Naso/oropharyngeal specimens RT-qPCR results of detect SARS-CoV-2 |
| Outcomes | Diagnostic accuracy, specificities, and negative predictive values analysis |
| Timings | From inception to August 2021 |
| Study design | A systematic review and meta-analysis |
COVID-19: coronavirus disease-19, RT-qPCR: reverse transcription quantitative polymerase chain reaction, SARS-CoV-2: severe acute respiratory syndrome coronavirus-2