Table 4

- Comparison of the groups in terms of native thiol, total thiol, disulfide, disulfide/native thiol, disulfide/total thiol, native thiol/total thiol levels, albumin.

TimeLow-flow group (n=32)Mid-flow group (n=25)High-flow group (n=25)P-value1
Mean±SD
Native thiol
T1248.17±64.30243.66±40.82371.65±66.33§<0.001*
T2229.18±58.06257.37±71.45342.10±47.78§<0.001**
T3242.27±55.64†,‡298.74±99.87371.71±67.08<0.001**
P-value20.183**0.141**0.014** 
Total thiol
T1268.66±72.30268.93±43.14394.96±69.18<0.001**
T2247.17±61.31275.23±73.88370.67±53.79<0.001**
T3260.83±59.00†,‡319.61±103.00393.61±70.77<0.001**
P-value20.181**0.178**0.224** 
Disulfide
T110.25±6.2912.22±6.7811.66±4.960.461*
T28.99±4.808.14±4.2314.28±7.420.001*
T39.30±5.5311.07±4.4110.94±5.550.387*
P-value20.788**0.383**0.140** 
Disulfide/native thiol percentage
T14.03±2.025.07±3.11§,†3.18±1.380.019*
T24.08±2.233.34±1.65§4.17±2.260.334**
T33.89±2.333.97±1.782.98±1.450.164*
P-value20.900**0.038**0.172** 
Disulfide/total thiol percentage
T13.67±1.504.48±2.522.97±1.190.025**
T23.69±1.863.09±1.463.77±1.980.366**
T33.53±1.943.63±1.502.65±1.390.094*
P-value20.092**0.297**0.169** 
Native thiol/total thiol percentage
T192.65±3.4091.91±7.6794.06±2.390.305*
T292.61±3.7293.81±2.9290.40±12.010.262*
T392.93±3.8792.74±3.0094.44±2.520.162*
P-value20.092**0.064**0.304** 
Albumin
T13.03±0.472.97±0.353.78±0.17<0.001*
T22.97±0.513.05±0.49†3.73±0.17<0.001*
T33.070.483.40±0.723.80±0.16<0.001*
P-value20.335**0.205**0.332** 

*Kruskal-Wallis test (Post hoc: Mann-Whitney U-test), **One-Way ANOVA test (post hoc: Bonferroni), §p-value2 of <0.05 (compared to T1-T2, native tiol, high-flow group), p-value1 of <0.05 (compared to high flow group, disulfide level at time T2 in mid-flow and low flow group), §†p-value2 of <0.05 (T2 compared to T1, disulfide/native thiol percentage), T1: pre-induction, T2: 60th minute after induction, T3: postoperative 2nd hour, SD: standard deviation